Open J Psychiatry Allied Sci. 2025 Dec 15. Epub ahead of print.
A case report on subacute sclerosing panencephalitis (SSPE) from an Indian tertiary care system.
Sarma N, Das H.
Abstract
A prolonged measles virus infection is the cause of the unusual slow-progressing degeneration of the central nervous system known as subacute sclerosing panencephalitis (SSPE). This illness usually manifests in the early stages of adolescence, progresses slowly, and has a dismal prognosis. Usually, there is a six to eight years latent interval between measles infection and SSPE. It progresses gradually and finally results in death. The measles virus may induce an aberrant immune response that results in inflammation of the brain and this serious disease. Because SSPE is uncommon and sometimes misunderstood, it can be exceedingly challenging to diagnose. To arrive at a diagnosis, a complete examination and a full history are required. Here we have presented a case of 12 years old girl with SSPE who visited a tertiary care hospital in Assam, India.
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