Open J Psychiatry Allied Sci. 2021 Mar 2. Epub ahead of print.
Marchiafava-Bignami disease: a rare neuropsychiatric sequelae of alcohol dependence syndrome in a tertiary care hospital in South India.
Das K, Arun PVSS, Ryali VSSR.
Abstract
Marchiafava-Bignami disease (MBD) was an entity that was discovered only upon autopsies of afflicted individuals. Magnetic resonance imaging (MRI) is now the most sensitive tool to diagnose MBD in vivo. Most common aetiology remains alcohol dependence with malnutrition, and a type A and B have been delineated. We present a case of MBD in chronic alcohol dependence, treated with parenteral thiamine wherein early clinical suspicion proved fruitful and there was significant recovery in the patient.
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